The Bettersizer 2600 can detect particle size using either the wet or dry method. This adaptable, powerful analyzer’s modular design and unique technologies have made it suitable for various applications. Users can easily and precisely assess materials ranging from 0.02 μm to 2600 μm.
Features and Benefits
- The wet and dry method of particle size is appropriate for a wide range of dispersing particle systems.
- A new patented method that uses both Fourier and Inversed Fourier optical systems allows for precise measurement of both large and small particles over a wide range.
- Optical bench with 92 detectors covering an angular range of 0.016°–165° Optional wet or dry dispersion.
- Small volume dry dispersing module for small sample volumes, notably pharmaceuticals or valuable samples in low supply.
- Easy to implement, create, and use Standard Operation Procedures for new materials.
- Measure the refractive index to get a more precise parameter for calculating the findings.
- Technology: Laser diffraction
- Particle size range: Wet dispersion: 0.02 to 2,600 μm Dry dispersion: 0.1 to 2,600 μm
- User-friendly software that is easy to learn how to use.
- Easy and fast to changeover between dispersing modules
Bettersizer 2600 | Laser Diffraction Particle Size Analyzer (Wet & Dry)
Video Credit: Bettersize Instruments Ltd.
Overview
Features
1. Fourier and Inverse Fourier Optical System
The Bettersizer 2600 is superior because it combines Fourier and inverse Fourier designs. This design allows for the detection of scattered light across a broad angular range from 0.016° to 165°. Additionally, unlike inverse Fourier design, particles do not need to be on a single plane, enabling accurate measurement of both small and large particles simultaneously.
Features of the Combination of Fourier and Inverse Fourier Design
- Spherical detector array: Forward, lateral, and backward detectors in 92 pieces in total
- Super large Fourier lens
- Small footprint: Compact design to save space
Image Credit: Bettersize Instruments Ltd.
2. Intuitive and Powerful Software
- Fully automatic measurement routine
- Automatic cleaning routine
- Automatic data backup and highly customizable reports
- Direct conversion according to Fraunhofer and Mie evaluation models
- Switch between wet and dry dispersion modules with one click
- Intuitive user interface and orderly operation
- Real-time PSD curve for determining the optimal measurement conditions
3. Wet Dispersion
The BT-802 is designed for particle size measurement with water as the medium.
Image Credit: Bettersize Instruments Ltd.
The BT-802 is constructed with an ABS shell and features various components such as a centrifugal pump, a peristaltic pump, an ultrasonic disperser, pinch valves, and a control circuit. Its stirring speed can be adjusted between 300 - 2500 r/minute. Additionally, it includes a built-in ultrasonic system (50 W) that aids in separating weak agglomerates.
BT-802 Automatic Wet Dispersion Module. Image Credit: Bettersize Instruments Ltd.
BT-80N is designed for particle size measurements using organic solvents as the media. BT-80N is suited for common organic solvents, including:
Source: Bettersize Instruments Ltd.
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Ethanol |
Methanol |
Isopropanol |
Ether |
Toluene |
Xylene |
Dichloromethane |
Octane |
Ethyl acetate |
Acetone |
Methyl oleate |
NMP solvents |
The BT-80N is comprised of a stainless-steel shell. Its components comprise a centrifugal pump, an ultrasonic disperser, a PTFE pipeline, a sintered-quartz sample cell, and a control circuit.
BT-80N Anti-corrosive Wet Dispersion Module. Image Credit: Bettersize Instruments Ltd.
Image Credit: Bettersize Instruments Ltd.
The BT-804 is tailored for measurements of valuable or small-volume samples, compatible with solvent or water as the medium. This unit includes an ABS shell, a stirring motor, an 8 ml cuvette, and a stirrer, among other components.
- Maximum capacity is 8 mL, and sample mass ranges from 0.005 to 0.1 g
- Applicable to samples dispersed in an organic phase or water
BT-804 Wet Small Volume Dispersion Module. Image Credit: Bettersize Instruments Ltd.
Image Credit: Bettersize Instruments Ltd.
4. Dry Dispersion
BT-902 is appropriate for dry powder measurements. The gas utilized can be compressed air, nitrogen, or another noble gas.
BT-902 is made up of an electromagnetic vibration feeder, a venturi pipe, a gas circuit, an electric circuit, a pressure sensor, etc.
BT-902 Automatic Dry Dispersion Module. Image Credit: Bettersize Instruments Ltd.
BT-903 is engineered for the particle size assessment of valuable and small quantities of dry powders, requiring a minimal sample volume of 20 mg. It consists of a venturi pipe, a gas circuit, an electric circuit, and a sample tube, among other components.
BT-903 Dry Small Volume Dispersion Module. Image Credit: Bettersize Instruments Ltd.
Image Credit: Bettersize Instruments Ltd.
5. Applications
Image Credit: Bettersize Instruments Ltd.
SOP
1. Standard Operating Procedure (SOP)
SOP is an easy approach for automated and standardized testing that guarantees operator-independent of the measurement results, increasing the objectivity and dependability of the results.
2. Advantages
- The Bettersizer 2600 provides an easy solution for standardized and automated testing.
- It assures that measurement findings are operator-independent, objective, and reliable.
Image Credit: Bettersize Instruments Ltd.
Performance
High Resolution and Sensitivity
The resolution and sensitivity of the Bettersizer 2600 are seen below: Sample A was gradually added to sample B, and the graph was altered accordingly.
Sample A < Sample B. Image Credit: Bettersize Instruments Ltd.
Sample A = Sample B. Image Credit: Bettersize Instruments Ltd.
Sample A > Sample B. Image Credit: Bettersize Instruments Ltd.
Technology
Laser Diffraction. Image Credit: Bettersize Instruments Ltd.
Particle size distribution is a key factor in various applications involving powders or dispersions, such as construction materials (including cement and sand), pharmaceuticals, ceramics, colored pigments, fertilizers, emulsions, and others.
As applications diversify, there is a corresponding increase in the requirements for measurement methods, including broader size ranges, faster measurement times, and improved reproducibility.
Measuring particles near the extremes of their size range, especially when attempting to detect both small (in the nanometer range) and large particles (in the lower millimeter range) in samples with polymodal or broad distributions, poses significant challenges.
Nonetheless, contemporary laser diffraction particle size analyzers like the Bettersizer S3 Plus navigate these obstacles with an innovative optical system. This system excels in detecting backscattered light from very small particles and capturing large particles using an integrated high-speed CCD camera or through a synergistic approach combining laser diffraction and image analysis methods.
Specification
Source: Bettersize Instruments Ltd
Bettersizer 2600 |
Particle size distribution |
Suspensions, emulsions, dry powders |
General |
Principle |
Laser diffraction technology |
Analysis |
Mie scattering theory and Fraunhofer diffraction theory |
Typical measurement time |
Less than 10 seconds |
Measurement performance |
Measuring range |
0.02 - 2600 μm (wet) *
0.1 - 2600 μm (dry) * |
Accuracy error |
≤ 0.5% * |
Repeatability |
≤ 0.5% * |
Number of size classes |
100 (user adjustable) |
Feeding mode |
Automatic circulation or micro cuvette (wet)
Gas transportation (dry) |
Special functions |
SOP settings, refractive index measurement, sample ratio calculation |
Main device |
Optical system |
Combined Fourier and inverse Fourier & Tilted sample cell |
Laser |
High-power optical fiber laser (10 mW / 635 nm) |
Detector |
92 detectors (forward, lateral and backward arrangements) |
Measuring angle |
0.016 - 165° |
Wet dispersion module |
Measurement method |
One-click operation (automated measurement, cleaning, saving, printing, etc.) |
Dispersion medium |
Water or organic solvents (sample dependent) |
Circulation speed |
300 - 2500 r/min |
Ultrasonication |
Dry burning prevention, 50 W |
Dry dispersion module |
Dispersion medium |
Air/ Nitrogen/Noble gas |
Air pressure |
0.1 - 0.8 MPa (Air compressor dependent) |
Software |
Conformity |
21 CFR Part 11, ISO 13320, USP <429> |
Reports |
Customizable reporting |
System parameters |
Dimensions (L x W x H) |
70.5 x 31.8 x 29.5 cm |
Weight |
23 kg |
Supply voltage |
100 - 240 V, 50/60 Hz |
Computer configuration (recommended) |
Computer interface |
At least one high-speed USB 2.0 or USB 3.0 port required |
Operating system |
Windows 7 (32 bit and 64 bit) or higher |
Hardware specification |
Intel Core i5 Processor, 4 GB RAM, 250 GB HD, Wide screen monitor |
*Sample and sample preparation dependent
Accessories
1. Sample Dispersion Modules
Source: Bettersize Instruments Ltd
Sample Dispersion Modules |
BT-802 |
BT-804 |
BT-80N |
BT-902 |
BT-903 |
Sample Dispersion |
Wet method |
Wet & small volume |
Anti-corrosive |
Dry method |
Dry & small volume |
Dispersion Modules |
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Combine with Main Device |
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Volume |
600 mL (dispersion medium) |
8 mL (dispersion medium) |
80 mL (dispersion medium) |
0.2 - 10 g (sample) |
0.02 - 1 g (sample) |
Automation |
Fully automated |
Semi-automated |
Semi-automated |
Fully automated |
Fully automated |
2. BT-A60 Autosampler
Introduction
The BT-A60 is a reliable, automated, and high-throughput sampling system. It provides maximal laboratory automation for sample measurements, lowering labor costs while increasing productivity and efficiency.
The small design saves bench space while measuring up to 60 samples in a single run. The BT-A60, which is compatible with the Bettersizer S3 Plus and Bettersizer 2600, provides 24/7 completely automated sample analysis for a variety of analytical applications.
Features
- Measurement automation
- Small footprint
- Accurate sample identification
- Efficient ultrasonic cleaning
- Up to 60 samples in one click
Image Credit: Bettersize Instruments Ltd.
Benefits
Source: Bettersize Instruments Ltd
Manual Insertion vs Measurement Automation |
Skilled operator required |
Save labor costs |
Potential risk of human error |
Independent of human error |
Risk of cros-contamination |
No risk of cross-contamination |
Messy workbench |
Well-organized workbench |
Longer sample-to-sample run times |
Shorter sample-to-sample run times |