Posted in | Spectrophotometers

NanoDrop™ Ultra Microvolume UV-Vis Spectrophotometer and Fluorometers for Laboratory Workflows

The Thermo Scientific NanoDrop Ultra Spectrophotometer and Fluorometers enable scientists to measure and evaluate nucleic acids and proteins with greater accuracy, speed, and reliability.

Thermo Scientific's NanoDrop Ultra Spectrophotometers and Fluorometers are the next generation of microvolume detection. This advanced equipment provides high accuracy and sensitivity for nucleic acid and protein analysis with sample quantities as low as 1.0 μL.

The NanoDrop Ultra aims to boost processes in a variety of domains, including genomics, proteomics, molecular biology, biotechnology, pharmaceuticals, and life sciences research. It offers unrivaled precision, efficiency, and reliability in a single compact device.

Thermo Scientific NanoDrop Ultra Microvolume UV-Vis Spectrophotometers and Fluorometers provide unprecedented insight into sample quality, preventing costly workflow hiccups.

Thermo Scientific’s Acclaro Sample Intelligence technology improves measurement accuracy and contaminant detection. Quantify and certify DNA, RNA, and protein samples in seconds with only 1–2 μL. Get full-spectral data before using it in downstream applications. Cuvette-compatible variants are also available for further versatility.

The NanoDrop Ultra spectrophotometers, with their compact design and large, high-resolution 10.1 in. touch screen interface, are an excellent choice for users seeking flexibility and convenience.

The optional Acclaro Pro software, which is compatible with the NanoDrop Ultra equipment, improves accuracy for highly concentrated samples through an improved algorithm. This is the next-generation NanoDrop single-channel instrument, featuring better hardware and software features than the popular NanoDrop 2000/2000c and NanoDrop One/OneC Spectrophotometers.

Acclaro Sample Intelligence Technology

  • Contaminant detection and analysis: Provides a full evaluation of sample purity while also correcting sample absorbance, allowing users to accurately identify, measure, and reduce contaminants. Plant and bacteria DNA and RNA differentiations are available to researchers, scientists, and professionals in agriculture, plant biology, microbiology, and genetic engineering
  • Sample integrity insight: Sends real-time notifications when bubbles are discovered in the sample, which could otherwise result in false readings
  • Reliable accuracy: uses digital image analysis and embedded sensors to guarantee measurement integrity

Tools to Aid in 21 CFR Part 11 Compliance

The optional Thermo Scientific SciVault 2 software provides laboratories with the resources they need to adhere to US FDA 21 CFR Part 11 and may be installed on the device or a companion PC.

  • Easy compliance: SciVault 2 manages user accounts, user account access, digital signatures, and audit logs by integrating with the NanoDrop Ultra software user interface
  • On-board options: Users can connect their instrument to the domain to utilize their Windows account management, or they can use on-board user account management to execute applications directly on the local instrument
  • Centralized solution- Install SciVault 2 software on a centralized computer to manage privileges and see audit records for numerous NanoDrop Ultra equipment in various laboratories

Streamlined Workflow

  • Fully integrated qPCR recipe calculator - users can use the built-in kit library or add their own favorites to have the software do the math for them. The qPCR recipe calculator recommends how to prepare the reaction based on the sample concentration
  • Auto-Measure and Auto-Blank features: Immediate measurements that take place when the pedestal arm is down can simplify multi-sample processing. One tap on the screen can activate or deactivate these features

Advanced Connectivity for Data Storage, Printing and Sharing

  • Export to the cloud: Export data directly to popular cloud storage services such as Microsoft OneDrive, Google Drive, and Thermo Fisher Connect
  • Direct LIMS integration: An integrated RESTful API allows users to submit data directly into the LIMS
  • Easy data-to-printer options: Print findings directly from the NanoDrop Ultra instrument via Wi-Fi, Ethernet, or a USB printer connection, or use the Nanodrop Ultra PC Control software to print exported data from the PC
  • Data User’s Way: Customize and evaluate the information in the data file before exporting to ensure that it fulfills any downstream requirements

Accuracy Beyond Expectations with the Acclaro Pro Software

This optional software package comprises updated versions of popular measurement applications that are unlocked from the factory, enabling ±5 % error over the absorbance dynamic range.

  • Precise high concentration measurements: Absorbance measurements within 5 % error up to 550 Abs (10 mm equivalent) up to 400 mg/mL IgG or 18,000 ng/μL
  • Quick dilution-free process: In two minutes, take three measurements on the pedestal
  • Enhanced calibration: Bundled purchases include an additional calibration from the factory to ensure remarkable accuracy in Acclaro Pro applications

This is solely for research purposes, not diagnostics.

Specifications

Source: Thermo Fisher Scientific - UV-Vis Spectroscopy

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Certifications/Compliance All NanoDrop instruments are approved to CE and UL/CSA.
Compatibility DYMO 550 Turbo printer, Bluetooth keyboard, mouse and barcode reader
Concentration dsDNA: Pedestal: 27,500 ng/μL BSA (IgG): Pedestal: 820 (400) mg/mL
Connections 2x USB-A Ports, 1x USB-C Port, Ethernet, Bluetooth, Wi-Fi
Detection Range dsDNA: Pedestal: 1.0 ng/μL, Cuvette: 0.2 ng/μL, BSA (IgG): Pedestal: 0.03 (0.015) mg/mL, Cuvette: 0.006 (0.003) mg/mL
Dimensions (L x W x H) 12.6 x 7.1 x 11.0 in (32 x 18 x 28 cm)
For Use With (Application) Nucleic Acid A260, A260/A280, A260/A230 and Labeled Nucleic Acids, Oligos;, Protein A280 and A205, Protein Pierce 660, Protein Bradford, Protein BCA, Protein Lowry, Labeled Proteins, OD600, UV-Vis, and Custom Methods, Acclaro Pro Applications
Includes ND Ultra Microvolume Spec
Keypad Built-in touchscreen
Measurement Time Standard: ≤7 sec Acclaro Pro: ≤30 sec
Pathlength 0.030 to 1.0 mm (auto-ranging)
Photometric Accuracy 3 % at 0.97 A, 302 nm, (Absorbance expressed at Abs/mm at 25 °C)
Photometric Range 10 mm equivalent: Pedestal: 0-550 A, Cuvette: 0-1.5 A
Power Consumption Operating: 15 W; Standby: 7 W
Processor Custom Linux
Repeatability Typical: 0.002 A (1.0 mm path) or 1 %CV, whichever is greater (SD of 10 individual measurements at 0.97 A)
Sample Volume (Metric) Min 1 μL
System Requirements Windows 10 or Windows 11
Warranty 2 Years
Wavelength Accuracy ±1 nm
Weight (English) Approximately 9.0 Ib.
Weight (Metric) 4.1 kg
Detector Type 2048-element CMOS Linear Image Sensor
Display 10 in. High Definition Color Display
Languages Chinese, English, French, German, Japanese, Spanish, Polish, Italian, Korean
Light Source Xenon Flash
Product Line NanoDrop
Spectral Bandwidth 1.8 nm
Voltage 12 VDC
Wavelength Range 190 to 850 nm
Unit Size Each

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