As for the flow rate of the liposome extrusion process, the greater the membrane’s surface area, the higher the flow rate. The GOE-142MM is a pilot-scale liposome extrusion system. It makes use of polycarbonate filter membranes with a large diameter of roughly 142 mm, which allow for a high flow rate and boost extrusion performance.
Genizer GOE-142MM, Online Liposome Extruder. Image Credit: Genizer LLC
Liposome with PEGylated Lipids
The Genizer Online Extruder (GOE-142MM) that combine with a microfluidic homogenizer, such as the NanoGenizer or HandGenizer. When the GOE-142MM is used in conjunction with the NanoGenizer homogenizer, researchers can decrease the number of passes required to attain a perfect liposome size distribution and desired particle sizes since the NanoGenizer system’s diamond interaction chamber will help pre-treat the liposome sample to the nanoscale.
NanoGenizer with GOE-142MM Liposome Extruder. Image Credit: Genizer LLC
- Capacity: 3,000 mL
- Filter diameter: 142 mm
- Cooling: Jacketed cooling ports
- Material: 316L stainless steel, NBR or Viton
- Spares: O-rings, collection silicone tubing
- Other Applications: Large pore support screen, laser micro pore disc